ADHFE1 and Renal neoplasm: In this study, we performed integrative analysis of bulk and single cell RNAseq data from renal tumors and normal kidney tissues, and nominated candidate biomarkers of HOT, L1CAM and LINC01187, which are also lineage-specific markers labeling the principal cell (PC) and intercalated cell (IC) lineages of the distal nephron, respectively.