Even though the overall ratio of L1CAM+ tumor and LINC01187+ tumor is roughly 1 to 1, we observed focal variations of L1CAM+ and LINC01187+ tumor compositions, including L1CAM+ dominant colonies (>75% L1CAM+, Supplementary Figure 7 A, B), mixed colonies (~50% L1CAM+ & 50% LINC01187+, Supplementary Figure 7 C, D), and LINC01187+ dominant colonies (>90% LINC01187+, Supplementary Figure 7 E, F) within the same tumor. The gene discussed is L1CAM; the disease is neoplasm.