Interestingly, we found that S100A9, CFH, PPP1R16A, POP4, PRDX6, UGT2B15, LDHA, TMEM106C, ALAS1, RTN3, and DNAJB4 were significantly upregulated in HCC tumor tissues compared to normal tissues (Figure 13). The gene discussed is POP4; the disease is hepatocellular carcinoma.