The observed change in surfactant production and AT2 cells may suggest that CGRP exposure plays a role in the re‐epithelialization process in ex vivo slices, which has been shown in several other PCLS models relating primarily to idiopathic pulmonary fibrosis (Kiener et al., 2021; Ptasinski et al., 2021). Here, CALCA is linked to idiopathic pulmonary fibrosis.