BCL2 and systemic lupus erythematosus: These findings were not correlated with disease activity for Bcl-2 and Bcl-XL expression, while active SLE patients (SLEDAI-2k ≥ 6 with a clinical SLEDAI-2k (excluding laboratory results) score ≥ 4) showed reduced Mcl-1 expression compared to SLE patients in remission (Fig. 1F).