Specifically, MMP7 changed consistently with NRCAM across pseudotime (Fig. 7F), MMP14 expression was consistent with NRCAM in LCSCs but was reactivated in mature HCC (Fig. 7G), whereas MMP9 expression did not appear to be associated with NRCAM (Fig. 7H). This evidence concerns the gene MMP9 and hepatocellular carcinoma.