In our study, NRCAM had the highest specificity of the three biomarkers (89.88%, versus 47.46% for AFP and 78.53% for PIVKA-II), NRCAM had a sensitivity of 47.46% (Table 5), which indicates that NRCAM may have utility for the prediction of a particular type of HCC. The gene discussed is AFP; the disease is hepatocellular carcinoma.