Most HCC cells (6642 cells) with activated NRCAM also had WNT/β-catenin signaling pathway (WNT7A, CTNNB1 co-activated) and EMT (Vimentin and CDH2 co-activated) activation (Fig. 7J), which was consistent with the scRNA-seq results. This evidence concerns the gene CDH2 and hepatocellular carcinoma.