In this study, we identify a circRNA derived from exons 5, 6, 7 and 8 of heterogeneous nuclear ribonucleoprotein U (hnRNPU), an oncogene with multiple important functions [15], which is termed as circ-hnRNPU that acts as a tumor suppressor in glycosylation and progression of gastric cancer. This evidence concerns the gene HNRNPU and gastric cancer.