MGAT1, one protein contributing to N-glycan synthesis, promotes the proliferation and migration of glioma or Wilms' tumor cells via N-glycosylation and up-regulation of GLUT1 [30] or mucin 3A [37], while inhibition of MGAT1 expression suppresses the growth and metastasis of breast cancer [38]. The gene discussed is MUC3A; the disease is central nervous system cancer.