FGFR1 and posterior cortical atrophy: Artificial overexpression of miR-4687-5p by mimics significantly decreased the expression of FGFR1 mRNA and protein in PCa cells, which could be reversed by artificial circFGFR1int2 overexpression (Fig. 8A), indicating that circFGFR1int2 supressed the effects of miR-4687-5p.