PCR results showed that circFGFR1int2 and FGFR1 mRNA were significantly overexpressed in PCa cells 22Rv1, LNCap, PC-3, and DU145, as compared to the normal prostate cell RWPE-1 (Fig. 2A) and BPH tissues (Fig. 2B). The gene discussed is FGFR1; the disease is posterior cortical atrophy.