Exposure of melanoma cells to IFNs markedly enhanced the basal expression of HLA-ABC and β2m compared to untreated cells utilized as control of the basal expression level (mean fold change respectively of 1.53 ± 0.56 and 1.24 ± 0.34 with IFN-α; 1.65 ± 0.88 and 1.18 ± 0.39 with IFN-γ) (Fig. 4B). This evidence concerns the gene IFNG and melanoma.