AKT1 and urinary bladder cancer: The miR-106a-5p miRNA, has a strong connection to the regulation of CD4 + T-cells and functions as a tumor suppressor, and miR-125b-5p is interrelated with suppressing PI3K/AKT pathway in bladder cancer [79] and the miR-125a-5p is connected with the macrophages inflammatory response [80].