It’s worth noting that both the reported Dnali1 cKO male mice and our Dnali1−/− mice display male infertility, damaged sperm motility, and disorganized fibrous sheath structure (Figs. 1F, 2E, F, 3E) [16]; these phenotypes recapitulate the reported phenotypes of the DNALI1-mutated infertile man [15]. Here, DNALI1 is linked to Infertility.