POSTN and cardiovascular disorder: Accumulating evidence underpins the putative role of periostin in the development of several cardiovascular diseases, including cardiac fibrosis [14, 15], atrial fibrillation [16], aortic dissection [17], acute myocardial infarction [18], arterial calcification [19], atherosclerosis [20], and pulmonary arterial hypertension [21, 22].