Their study, however, does not unequivocally discuss how exactly are C1-INH-HAE and nC1-INH-HAE patients divided in their population, and 6/10 of the patients who had an HAE attack after the vaccine had a poor AECT (Angioedema Control Test) result, which may convey more frequent HAE attacks or that the attacks are more difficult to treat with the applied therapy36,37. The gene discussed is SERPING1; the disease is hereditary angioedema.