CD8A and neoplasm: The results showed that in the immune infiltration classification of LUAD patients, PBK high expression group was higher in C1 and C2 types, which were mentioned in other studies as having high proliferative features and associated with Th2 cell bias, M1/M2 macrophage polarization and CD8 signaling, while PBK low expression was higher in C3 inflammatory subtypes, while C3 types had low to moderate tumor cell proliferation and lower levels of altered somatic cell copy number than other subtypes characterized (Fig. 5B, F)37.