SPTBN2 and cerebellar disorder: We found that the chromatin at the mutation location was open in RL progenitors, granule cells and GABAergic cells for SPTBN2 and only in microglia for PLEKHG4 in the developing human cerebellum, indicating that cerebellar disorders may be associated with not only cell type-specific gene expression profiles but also chromatin accessibility states (Fig. 6b, c).