CD4 and viral infectious disease: Viral infection related neutrophil profiles negatively correlated with CD4+ T cell (−0.67 in cases, −0.78 in controls) and B cell (−0.67 in case, −0.87 in controls) profiles in both cases and controls, but the negative correlation between neutrophils and CD8+ T cells was detected only in controls (−0.66 in controls, −0.13 in cases) (Fig. 3d, e).