Some authors proposed that the MTOR-RPS6KB-EIF4EBP signal transduction pathway might be a target for an anti-HD drug based on autophagy stimulation [34], though further studies are required to demonstrate the efficacy of such a potential therapeutic option, and the role of AMPK in autophagy induction cannot be underestimated in this case [35]. The gene discussed is MTOR; the disease is Huntington disease.