The most common positive results in this cohort of patients with only a PH of LC were in BRCA2 (3.4%, n = 70/2,040), EGFR (2.1%, n = 34/1,589), and ATM (2%, n = 40/1,975; Fig 3B, Data Supplement, Table S3). Here, ATM is linked to laryngotracheoesophageal cleft.