The GO and KEGG function enrichment analysis of genes with the top 500 R‐values and p < 0.05 demonstrated that the expression of TTC7B in HNSCC was associated with cell migration, FAs, cell shape, etc. Given the significant role of FAs‐related genes in tumor cell invasion and migration, we further investigated the relationship between TTC7B expression and FAs‐related pathways in HNSCC using GSVA.16 The gene discussed is TTC7B; the disease is neoplasm.