PRKN and Parkinson disease: Consistent with this hypothesis, plasma PINK1, Parkin, and PGAM5 concentrations were significantly higher in PD (97.0 ± 20.5 ng/mL, 22.6 ± 4.67 ng/mL, 910 ± 147 pg/mL, respectively) and PDs (92.0 ± 17.0 ng/mL, 22.4 ± 3.45 ng/mL, 842 ± 150 pg/mL, respectively) as compared to the HC group (74.4 ± 14.7 ng/mL, 17.7 ± 3.96 ng/mL, 697 ± 167 pg/mL, respectively) (Table 2 and Figure 2A–C).