To further validate the relationships among the expression levels of NURR1, miR-30e-5p, NLRP3 and IL-1β in PD patients, we conducted an analysis using Spearman's coefficients to examine the correlations between PBMC NURR1, miR-30e-5p and NLRP3 expression levels, as well as plasma IL-1β level. This evidence concerns the gene NLRP3 and Parkinson disease.