The results showed that the combination of NURR1, miR-30e-5p, and NLRP3 exhibited superior AUCs for PD, with a value of 0.82 (95% CI, 0.764–0.88, p < 0.01), compared to individual biomarkers (NURR1, miR-30e-5p, NLRP3, and IL-1β) or other combinations (Fig. 3B, C). Here, NLRP3 is linked to Parkinson disease.