Representative IHC staining for CDK5 low and high expression is shown in Fig. 6B. The histogram shows low CDK5 expression in 62.6% (213/340) of the tumor samples, which is remarkably higher than that in adjacent nontumor samples (22.7%, 22/97, p < 0.001; Fig. 6B). This evidence concerns the gene CDK5 and neoplasm.