Consistently, we found elevated levels of ALKBH5 in both the whole peripheral blood mRNA (p < 0.01, Additional file 1: Fig. S2I) and plasma protein (p < 0.001, Fig. 2F and Table 3) in schizophrenia, indicating m6A modification dysfunction in schizophrenia. The gene discussed is ALKBH5; the disease is schizophrenia.