APP and early-onset autosomal dominant Alzheimer disease: We also observed few instances of MG/MDM positive for the presence of glycogen granules, which were abundant in MG strictly nearby amyloid beta plaques and dystrophic neurites in aged APP–PS1 male mice [27], indicating that SCI at this time point does not strongly induce nor reduce in MG/MDM near or far from the injury site the presence of glycogen granules, contrary to what has been previously observed in MG near amyloid beta plaques and dystrophic neurites in a mouse model of Alzheimer’s disease pathology [27].