STAT3 and gastric cancer: Our team focused on the neoadjuvant intraperitoneal and systemic chemotherapy (NIPS) of advanced GC with peritoneal metastases [12, 13], and our prior study have found HOXA11 is an activator of PM in GC and HOXA11 could form a positive feedback loop with Stat3 to regulate adhesion, motility and apoptosis/anoikis-resistance phenotypes of gastric cancer cells [1].