CD44 positive GC cells and HOXA11 positive GC cells in tumor fraction were significantly increased in the mice injected with NCI-N87-HOXA11 cells and HMrSV5 cells in comparison to those of mice injected with NCI-N87-Vector cells and HMrSV5 cells (P < 0.05) (Fig. 4G, I, J). This evidence concerns the gene HOXA11 and neoplasm.