Moreover, H&E, Masson and Picrosirius Red staining have clearly separated tumor fraction and stromal ones (Fig. 4E), and we clearly observed Egr1, α-SMA&HBME1-positive mesothelial cells in the stromal fraction, the Egr1 positive mesothelial cells in stromal fraction were obviously increased in the mice injected with NCI-N87-HOXA11 cells and HMrSV5 cells in comparison to those of mice injected with NCI-N87-Vector cells and HMrSV5 cells (P < 0.01) (Fig. 4F, H). Here, ACTA1 is linked to neoplasm.