HOXA11 served as a transcription factor in the nucleus and played crucial roles in the tumorigenesis of various types of cancer [1, 24], and the above results confirmed that HOXA11 could upregulate the mRNA and protein levels of PDGF BB and TGF β1, thus, we hypothesized that HOXA11 enhances the transcriptional activity of PDGF BB and TGF β1 promoters. This evidence concerns the gene HOXA11 and cancer.