This regulatory mechanism seems distinct in nutrient-dependent tissue remodeling, as it is dispensable during pathogenic infection, and potentially underlies differential metabolic control of STAT activation that could broaden function of the single STAT gene in Drosophila. In addition to influencing JAK/STAT signaling, our small-scale meta-analysis also suggests that Acbp6 may potentially have a role in chronic stress conditions, such as aging. The gene discussed is SOAT1; the disease is infection.