Their involvement in psoriasis, as both necessary and sufficient for plaque formation, identified IL-17-producing γδ T cells as promising therapeutic target.69–75 Notably, the pro-tumor role played by IL-17+γδ T cells in both mice76–79 and humans80,81 has significantly enhanced our understanding of the involvement of γδ T cells in tumorigenesis. This evidence concerns the gene IL17A and neoplasm.