For instance, although both subtypes share a suite of chemokine receptors on their surface, CCR5 is restricted to Vδ2 T cells, while CXCR1 is mainly expressed on Vδ1+ cells of circulating blood.188,190 In addition, tumor-infiltrating Vδ1+ cells highly express CXCR3.308 These findings suggest different tissue migratory patterns of Vδ1+ and Vδ2+ subsets when they receive inflammatory signals. This evidence concerns the gene CXCR3 and neoplasm.