IL17A and psoriasis: Furthermore, the application of scRNA-seq on the skin samples from patients holds the potential to shed light on the role that γδ T cells might play in the etiology and progression of psoriasis, providing valuable insights into their intricate involvement in the disease.454–457 Altogether, psoriasis is an autoimmune skin disorder driven by IL-17 overproduction, involving both Th17 and γδT17 cells.