JAK2 and acute lymphoblastic leukemia: We detected recurrent copy number variants (CNV) or single nucleotide variants (SNV) in CDKN2A/B, NRAS, KRAS, IKZF, JAK1, and JAK2 (Supplementary Fig. S2, Supplementary Fig. S2, and Supplementary Data S2), which are commonly mutated in pediatric ALL samples9.