GSDMD and infection: The data from the infection of 3D enteroids, enteroid-derived 2D monolayers (Fig. 4), the early (first 18 h p.i.)infections in GsdmD-deficient mice (Fig. 4), the later time point (48 h p.i.)infections with the BM chimeras (Fig. 5) and the epithelial-specific GsdmD∆/∆IEC experiments (Fig. 5) prove that epithelial GSDMD also contributes to restricting S.Tm, most likely during the initial phase of the infection.