Others found a similarity between the glycan structures on the SARS-CoV-2 S protein and the domains recognized by anti-A antibodies and hypothesized that the reduced viral infection may be the result of the antibody-mediated blockade of the interaction between the virus and the angiotensin-converting enzyme 2 (ACE2) receptor, thus preventing entry into the lung epithelium [22, 29]. This evidence concerns the gene PROS1 and viral infectious disease.