LGMN and central nervous system cancer: The results from the survival analysis of 3 groups of mice bearing glioma showed that AEP KD significantly prolonged overall survival (OS) from 23 to 28 days (P = 0.0005), while tDDX3X-C rescue in turn led to worsening and shortening of survival in the AEP KD group of mice (P = 0.0076) (Figure 4H).