IFNG and neoplasm: They account for approximately 30–50% of all lymphocytes, especially in the liver.12,13 NK cells with a wide range of receptors for cytokines are immediately recruited and activated by various cytokines to infected tissues, increasing their anti-infective and anti-tumor abilities.13,14 They also play an anti-fibrotic role by promoting apoptosis through production of interferon gamma (IFN-γ) and directly killing hepatic stellate cells (HSCs).15,16 However, it is known that the number and function of NK cells may be decreased due to ethanol and its metabolites during chronic alcohol intake.2,17