Among the evaluated inflammatory markers, interleukin-6 (Il6) was significantly overexpressed in the higher dose of KP13-treated CKD group, and tumor necrosis factor-α (Tnf) was overexpressed in both KP13-treated CKD groups compared to the sham-operated group (*p < 0.05) (Fig. 6C and D). The gene discussed is IL6; the disease is chronic kidney disease.