Chr 3: MIR124-2 host gene is the most abundant brain-specific miR, promotes microglial quiescence, inhibits microglial and astrocyte activation, and suppresses experimental autoimmune encephalomyelitis by deactivating macrophages via the CEBPA/C/EBP-a-SPI1/PU.1 pathway. This evidence concerns the gene CEBPA and experimental autoimmune encephalomyelitis.