Among the six proteins that had a fold change superior to 2 (Table 2), 5 were overexpressed in the A375ΔE2 cells and turned out to be known tumour (FAM107B, ACPP) or metastasis (NDRG1) suppressors [24,25,26,27], or transcription factors known to activate these proteins (p65, also known as NF-κB regulatory subunit RELA, is an activator of ACPP) [28]. The gene discussed is FAM107B; the disease is neoplasm.