In the context of the tumor-promoting actions of lncRNAs, Elsayed et al. revealed that the lncRNA PRKAR-1B AS2 promotes tumor growth and survival of ovarian cancer and that knockdown of PRKAR1B-AS2 by a specific siRNA reduced tumor growth and sensitized the response to cisplatin in both in vitro and in vivo mouse models of ovarian cancer. The gene discussed is PRKAR1B; the disease is neoplasm.