Markers of endothelial injury such as von Willebrand’s factor (VWF) and its cleaving protein, a disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 (ADAMTS13), also known as von Willebrand factor-cleaving protease (VWFCP), are also implicated in COVID-19 disease severity [107]. The gene discussed is VWF; the disease is COVID-19.