MMP16 and cancer: They are also relevant to the downregulation of SNAI2, Mal, T‐cell differentiation protein (MAL), RND3, LAMB1, CAV1, MMP16, SRPX, ITGB3, and TGF‐beta signaling pathway (BMP2) genes, which are reported to be relevant to metastasis, cancer progression, motility, invasion into the surrounding extracellular matrix, and the proliferation, and migration of PCa.24, 25