In a large multicentre study of GBA1 mutation carriers, GBA1 was also found to be associated with PDD, with an odds ratio of 6.48 (95% CI, 2.53 – 15.37) as well as DLB, with an odds ratio of 8.28 (95% CI, 4.78– 14.88), providing evidence that GBA1 mutations lead to impaired cognition in synucleinopathies [20]. Here, GBA1 is linked to Lewy body dementia.