AKT1 and Anxiety: AKT1 is one isoform of the AKT family, studies showed that AKT1 deficiency could impact anxiety-related behavior and fear memory extinction in mice and AKT1 is modified by mood stabilizers and psychotropic medicines.[28] Moreover, the crucial pathogeny of PTSD is the influence of fear memory.[31] It indicated that PTSD and anxiety are associated with AKT1.