Similarly, the odds ratio for PJP versus P. jirovecii-colonization was significantly elevated when the percentage of CD4+ T cells < 30%, CD8+ T cells > 40%, lymphocyte counts < 1.0×109/L, ESR > 15 mm/h, CD4+T/CD8+T < 1.4 or > 2.0, CRP > 10 mg/L, B cells < 9% of lymphocytes, and a history of treatment with glucocorticoids within 2 weeks. The gene discussed is CD4; the disease is pneumocystosis.