HADHA and ovarian cancer: Notably, the upregulation of HADHA was associated with decreased survival compared to patients exhibiting low expression of HADHA, as illustrated in Fig. 1B. Simultaneously, we detected elevated HADHA mRNA level in three ovarian cancer cell lines HO-8910, A2780 and SK-OV-3 cells, in comparison to normal ovarian epithelial cells IOSE80.