The mechanism could, therefore, be applied to develop novel pharmaceutical strategies for preventing the HGF nitration (Y198 and Y250) in human/pet/animal health sciences to: combat age‐related muscle atrophy with impaired regeneration (including sarcopenia and frailty), guide the extension of healthy life expectancy, and importantly in improving animal welfare and sustaining food security through meat‐animal production. The gene discussed is HGF; the disease is sarcopenia.