MET and age: Finally, it is worth noting that the HGF/c‐met axis counteracts myocardial fibrosis (Gallo et al., 2015; Nakamura et al., 2005; Taniyama et al., 2000); thus, an additional negative effect of HGF nitration/dysfunction is the loss of its protective role as a potent antifibrotic factor; hence, HGF nitration/dysfunction is also expected to explain the progression of age‐related intramuscular fibrosis (see Figure S8D).