STAG1 and neoplasm: STAG2‐mutant tumor cells result in a switch from STAG2 to STAG1‐cohesin complexes, differential cohesin dependence on DNA damage repair, and an increased sensitivity to PARPi.[44] Moreover, STAG2‐mutated tumor cells are defective in HR repair upon depletion of STAG1, as evidenced by the HR‐defective score.[40] Exactly what function of STAG2 is important with respect to HR repair remains at this point poorly understood.