Breast cancer is the most common and second most lethal invasive cancer in women in the U.S.1 Breast cancer risk is shown to be impacted by a combination of both genetic and environmental factors2 including demographics such as age, race, reproductive age or history, weight, income, and location3–7, while survival can be impacted by the resulting tumor stage, morphology, histology, gene expression, and hormone receptor status3,8–11. Here, NR4A1 is linked to breast cancer.