After transplantation, the tumors resembled Papillary and Follicular tumors and, transcriptomics analysis suggested a cooperative effect of Kisspeptin receptor (KISS1R) and Tissue Inhibitor of Metalloproteinase 1 (TIMP1)/Matrix metallopeptidase 9 (MMP9)/Cluster of differentiation 44 (CD44), on tumor development and progression [54]. The gene discussed is MMP9; the disease is neoplasm.