TP53 and neoplasm: For example, miR-107 is a P53-associated regulator of cell cycle and proliferation, elevated in early stage liver cancer [69–72]; miR-124-3p is a tumor suppressor that regulates proliferation and invasion in liver cancer by inducing G1-phase cell-cycle arrest [73, 74]; and miR-103a-3p is a promoter of proliferation that is highly dysregulated in liver cancer [75].