INS and polycystic ovary syndrome: Metformin treatment resulted in significant decrease in the elevated insulin, glucose levels, and the HOMA‐IR in PCOS‐IR rats (fasting insulin, 11.8 ± 0.69; glucose, 8.3 ± 0.92; HOMA‐IR, 34.3 ± 0.63; p < 0.05).