It is an inhibitory protein during the lipid peroxidation process, capable of degrading small molecules or complicated peroxides.[45] There are several ways to induce tumor ferroptosis via focusing on GPX4, such as directly targeting GPX4, GPX4 enzymatic function inhibition, GPX4 deletion, etc.[31, 46] GPX inhibitors mainly include RSL3, FIN56, diphenyleneiodonium 7 (DPI7), DPI10 and endoperoxide‐containing 1, 2‐dioxolane (FINO2). The gene discussed is GPX4; the disease is neoplasm.