We cloned the above predicted position sequence into the Pgl3 vector with the firefly luciferase reporter gene vector and performed Dual‐luciferase reporter assay on MDA‐MB‐231 and HCC‐1806 shRNA‐NC and shIGF2BP2‐1 cell lines (Figure 6C,D). We then mutated the key m6A modification sites in A and B sequences and reconstructed the firefly luciferase reporter gene vectors for transfection. The gene discussed is SDHC; the disease is hepatocellular carcinoma.