While HBSS-injected animals showed highest ST2 expression on CD8+ and CD4+ T cells (Fig 3E), during infection we observed the highest proportion of ST2+ cells among Tregs (~8%), followed by Tconv (~2%), and CD45+Non-LymphoidCD11b- cells (~1%); the latter likely representing meningeal innate lymphoid type 2 cells (ILC2s) which are known to express ST2 [36] and exhibited the highest levels of ST2 by MFI (Figs 3F and S3F). Here, CD4 is linked to infection.